Research Priorities for Hip and Knee Replacement

Every year, about 150,000 hip and knee replacements are done in the UK because of osteoarthritis.  But we still don’t know enough about which patients benefit most, when is the best time for surgery and how do we ensure that patients recover quickly and well?

James Lind Alliance

A James Lind Alliance Priority Setting Partnership gathered research uncertainties from a wide range of people with osteoarthritis and health professionals that treat and look after them.  There were prioritised using a James Lind Alliance approach and the results and process to achieve the Top Ten Research Priorities are detailed in this report.

Cochrane Collaboration

Evidence in agenda setting: new directions for the Cochrane Collaboration

This paper is a commentary on published accounts and reviews of Research Priority and Agenda Setting exercises, that can inform the future direction of priority setting Systematic Reviews in Cochrane.

The authors critique the published accounts and assess where they add to our existing knowledge and understanding of priority setting and where there are gaps.  It suggests 6 key steps for Cochrane Collaborative Review Groups to improve their research priority setting strategies.  It also gives information about the Cochrane Prioritization Methods Group that was convened in November 2011 to address these methodological issues.

This paper was published in the Journal of Clinical Epidemiology in August 2012, authors Nasser M, Welch V, Ueffing E, Crowe S, Oliver S, Carlo R.

To find out more about Cochrane, click here, for more information the Cochrane Prioritization Methods Group click here.



Patient and Public Involvement Toolkit

Patient and Public Involvement Toolkit, Cartwright J, Crowe S, Feb 2011, BMJ Books Evidence Based Toolkit Series, Wiley Blackwell 9781405199100

Now that patient and public involvement is in the mainstream of healthcare, professionals at all levels from postgraduate trainee to consultant need to understand the issues and be able to collaborate with patients on joint initiatives.

This Toolkit answers all your questions about setting up your project, and seeing it through successfully.  In the concise, easy to follow format so popular in the Toolkit series, it guides you through the process step–by–step. Continue reading

The PRIME project

The PRIME project: developing a patient evidence base

Staniszewska S,  Crowe S,  Badenoch D, Edwards C , Savage J, Norman W.   Health Expectations, Vol 13, Issue 3, pages 312–322, September 20

The concept of evidence has become firmly rooted in health care, with most importance placed on the outcome of research in clinical and economic spheres. Much less emphasis is placed on the patient’s contribution to evidence which remains relatively vague, of low status and often difficult to integrate with other forms of knowledge. Continue reading


Recent publications

Patient and public involvement—“A smooth sea never made a skilled sailor”

Concannon TW, Grant S, Welch V, Petkovic J, Selby J, Crowe S, Synnot A, Greer-Smith R, Mayo-Wilson E, Tambor E, Tugwell P. Practical guidance for involving stakeholders in health research. J Gen Intern Med 2019;34(3):458–63. Epub ahead of print (with supplemental materials) 10.1007/s11606-018-4738-6.

Experiences and lessons in stakeholder engagement in environmental evidence synthesis: a truly special series Haddaway and Crowe Environ Evid (2018) 7:11

‘Who Inspired My Thinking? – Sherry Arnstein’. Crowe S, Research for All, 1 (1): 143-146. DOI 10.18546/RFA.01.1.10. (2017)

Research Priority Setting in organ transplantation: a systematic review. Tong A. Sautenet B, ChapmanJR, MacDonald P, Shackel N, Crowe S, Hanson CS, Hill S, Synnot A, Craig J.  Transplant International 30(4), 327-343.

Making patient relevant clinical research a reality Crowe S, Giles C BMJ 2016; 355 doi: (Published 23 December 2016) Cite this as: BMJ 2016;355:i6627

Nephrologists’ perspectives on defining and applying patient-centered outcomes in hemodialysis. Tong A, Winkelmayer WC, Wheeler DC, Van Biesen W, Tugwell P, Manns B, Hemmelgarn, Harris T, Crowe S, Ju A, O’Lone E, Evangelidis N, Craig JC. Clinical Journal of the American Society of Nephrology [Accepted 3rd November 2016]

Determining priorities for research to improve fundamental care on hospital ward Ball Jane, Ballinger Claire, De Iongh Anya, Dall’Ora Chiara, Crowe Sally, Griffiths Peter, Research Involvement and Engagement 2016, 2:31 DOI: 10.1186/s40900-016-0045-8

Identifying the most important outcomes for systematic reviews of interventions for rhinosinusitis in adults: working with Patients, Public and Practitioners.
Hopkins C, Philpott C, Crowe S, Regan S, Degun A, Papachristou I, Schilder AG.
Rhinology. 2015 Nov 15. [Epub ahead of print] PMID: 26569006

Standardised outcomes in nephrology – Haemodialysis (SONG-HD): study protocol for establishing a core outcome set in haemodialysis
Allison Tong • Braden Manns • Brenda Hemmelgarn • David C Wheeler • Peter Tugwell • Wolfgang C Winkelmayer • Wim van Biesen • Sally Crowe • Peter G Kerr • Kevan R Polkinghorne •Kirsten Howard • Carol Pollock • Carmel M Hawley • David W Johnson • Stephen P McDonald • Martin P Gallagher • Rachel Urquhart-Secord • Jonathan C Craig Trials 08/2015; 16(1):364. DOI:10.1186/s13063-015-0895-7 • 2.12

Assessing the extent to which current clinical research is consistent with patient priorities: a scoping review using a case study in patients on or nearing dialysis. Jun M, Manns B, Laupacis A, Manns L, Rehal B, Crowe S, Hemmelgarn BR (2015). Canadian Journal of Kidney Health and Disease. Vol 2 Issue1. 2015

Missed opportunities for impact in patient and carer involvement: a mixed methods case study of research priority setting. Snow R, Crocker JC, Crowe S Research Involvement and Engagement Journal July 2015 1845655987160084

Patients’, clinicians’ and the research communities’ priorities for treatment research: there is an important mismatch. Crowe, S. Fenton, M. Hall, M. Cowan K. and Chalmers I. (2015) Research Involvement and Engagement 2015 1:2